Invention Grant
US08623818B2 Glucagon receptor antagonists, compositions, and methods for their use
有权
胰高血糖素受体拮抗剂,组合物及其使用方法
- Patent Title: Glucagon receptor antagonists, compositions, and methods for their use
- Patent Title (中): 胰高血糖素受体拮抗剂,组合物及其使用方法
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Application No.: US12992771Application Date: 2009-05-13
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Publication No.: US08623818B2Publication Date: 2014-01-07
- Inventor: William J. Greenlee , Andrew Stamford , Michael W. Miller , Duane Eugene DeMong
- Applicant: William J. Greenlee , Andrew Stamford , Michael W. Miller , Duane Eugene DeMong
- Applicant Address: US NJ Rahway
- Assignee: Merck Sharp & Dohme Corp.
- Current Assignee: Merck Sharp & Dohme Corp.
- Current Assignee Address: US NJ Rahway
- Agent Anna L. Cocuzzo; Catherine D. Fitch
- International Application: PCT/US2009/043722 WO 20090513
- International Announcement: WO2009/140342 WO 20091119
- Main IPC: A61K38/28
- IPC: A61K38/28 ; A61K38/00

Abstract:
The present invention relates to compounds of general formula (I), wherein ring A, ring B, R1, R2, R3, Z, and L1 are selected independently of each other and are as defined herein, to compositions comprising the compounds, and methods of using the compounds as glucagon receptor antagonists and for the treatment or prevention of type 2 diabetes and conditions related thereto.
Public/Granted literature
- US20110065634A1 GLUCAGON RECEPTOR ANTAGONISTS, COMPOSITIONS, AND METHODS FOR THEIR USE Public/Granted day:2011-03-17
Information query
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