Invention Grant
- Patent Title: Blocking mesothelin peptide fragments
- Patent Title (中): 阻断间皮素肽片段
-
Application No.: US13133136Application Date: 2008-12-05
-
Publication No.: US08623828B2Publication Date: 2014-01-07
- Inventor: Mitchell Ho , Ira Pastan , Osamu Kaneko , Byungkook Lee
- Applicant: Mitchell Ho , Ira Pastan , Osamu Kaneko , Byungkook Lee
- Applicant Address: US DC Washington
- Assignee: The United States of America as Represented by the Secretary of the Department of Health and Human Services
- Current Assignee: The United States of America as Represented by the Secretary of the Department of Health and Human Services
- Current Assignee Address: US DC Washington
- Agency: Kilpatrick Townsend & Stockton LLP
- International Application: PCT/US2008/085743 WO 20081205
- International Announcement: WO2010/065044 WO 20100610
- Main IPC: C07K5/00
- IPC: C07K5/00
Abstract:
The present invention provides mesothelin peptide fragments corresponding to the CA125 binding site of mesothelin. The peptide fragments find use in disrupting the binding interaction between mesothelin and CA 125, for example, in the treatment and prevention of cancers that require the interaction of mesothelin and CA125 for growth, progression and/or metastasis.
Public/Granted literature
- US20110236385A1 BLOCKING MESOTHELIN PEPTIDE FRAGMENTS Public/Granted day:2011-09-29
Information query
