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US08623878B2 Use of allopurinol for the treatment of hand foot skin reaction 失效
使用别嘌呤醇治疗手足皮肤反应

Use of allopurinol for the treatment of hand foot skin reaction
Abstract:
Use of allopurinol or a pharmaceutically acceptable salt thereof for the treatment or prevention of Hand Foot Skin Reaction (HFSR) induced by Multitargeted Kinase Inhibitor (MKI) therapy. The allopurinol or its salt is administered topically to the affected areas, palms and soles, preferably in the form of a cream.
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