Invention Grant
US08623893B2 Pyridino-pyridinone derivatives, preparation and therapeutic use thereof 有权
吡啶并吡啶酮衍生物,其制备和治疗用途

Pyridino-pyridinone derivatives, preparation and therapeutic use thereof
Abstract:
The present invention relates to derivatives of pyridino-pyridinones, and to their preparation and use thereof, having activity as inhibitors of kinase activity of receptors for PDGF (platelet derived growth factors) ligands and optionally of receptors for the FLT3 (fms-like tyrosine kinase receptor) ligand receptors, said derivatives comprising compounds of formula (I): wherein the various substituent groups are more specifically defined herein. The compounds are suitable as therapeutics for the treatment of various proliferative diseases.
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