Invention Grant
- Patent Title: Modulators of ATP-binding cassette transporters
- Patent Title (中): ATP结合盒转运蛋白的调节剂
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Application No.: US12767472Application Date: 2010-04-26
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Publication No.: US08623905B2Publication Date: 2014-01-07
- Inventor: Sara S. Hadida Ruah , Peter D. J. Grootenhuis , Fredrick F. van Goor , Jinglan Zhou , Brian Bear , Mark T. Miller , Jason McCartney , Mehdi Michel Djamel Numa
- Applicant: Sara S. Hadida Ruah , Peter D. J. Grootenhuis , Fredrick F. van Goor , Jinglan Zhou , Brian Bear , Mark T. Miller , Jason McCartney , Mehdi Michel Djamel Numa
- Applicant Address: US MA Cambridge
- Assignee: Vertex Pharmaceuticals Incorporated
- Current Assignee: Vertex Pharmaceuticals Incorporated
- Current Assignee Address: US MA Cambridge
- Agency: Honigman Miller Schwartz and Cohn LLP
- Agent Heidi M. Berven; Jonathan P. O'Brien
- Main IPC: A61K31/404
- IPC: A61K31/404 ; C07D209/40
Abstract:
Compounds of the present invention and pharmaceutically acceptable compositions thereof, are useful as modulators of ATP-Binding Cassette (“ABC”) transporters or fragments thereof, including Cystic Fibrosis Transmembrane Conductance Regulator (“CFFR”). The present invention also relates to methods of treating ABC transporter mediated diseases using compounds of the present invention.
Public/Granted literature
- US20110060024A1 Modulators of ATP-Binding Cassette Transporters Public/Granted day:2011-03-10
Information query
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