Invention Grant
US08624011B2 Vaccines and immunotherapeutics comprising IL-15 receptor alpha and/or nucleic acid molecules encoding the same, and methods for using the same
有权
包含IL-15受体α和/或编码其的核酸分子的疫苗和免疫治疗剂及其使用方法
- Patent Title: Vaccines and immunotherapeutics comprising IL-15 receptor alpha and/or nucleic acid molecules encoding the same, and methods for using the same
- Patent Title (中): 包含IL-15受体α和/或编码其的核酸分子的疫苗和免疫治疗剂及其使用方法
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Application No.: US13391615Application Date: 2010-09-14
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Publication No.: US08624011B2Publication Date: 2014-01-07
- Inventor: David B Weiner , Kimberly A Kraynyak , Michele Kutzler
- Applicant: David B Weiner , Kimberly A Kraynyak , Michele Kutzler
- Applicant Address: US PA Philadelphia
- Assignee: The Trustees of the University of Pennsylvania
- Current Assignee: The Trustees of the University of Pennsylvania
- Current Assignee Address: US PA Philadelphia
- Agency: Pepper Hamilton, LLP
- International Application: PCT/US2010/048827 WO 20100914
- International Announcement: WO2011/032179 WO 20110317
- Main IPC: C07H21/04
- IPC: C07H21/04 ; C12N15/24 ; C12N15/11 ; C12N15/117 ; C12N15/33 ; C12N15/31

Abstract:
Compositions, recombinant vaccines and live attenuated pathogens comprising one or more isolated nucleic acid molecules that encode an immunogen in combination with an isolated nucleic acid molecule that encodes IL-15Ra or a functional fragment thereof are disclosed. Methods of inducing an immune response in an individual against an immunogen, using such compositions are disclosed.
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