Invention Grant
- Patent Title: ENA nucleic acid drugs modifying splicing in mRNA precursor
- Patent Title (中): ENA核酸药物修饰mRNA前体的剪接
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Application No.: US12847237Application Date: 2010-07-30
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Publication No.: US08624019B2Publication Date: 2014-01-07
- Inventor: Masafumi Matsuo , Yasuhiro Takeshima , Makoto Koizumi
- Applicant: Masafumi Matsuo , Yasuhiro Takeshima , Makoto Koizumi
- Applicant Address: JP Kobe-shi JP Kobe-shi JP Tokyo JP Tokyo
- Assignee: Masafumi Matsuo,Yasuhiro Takeshima,Daiichi Sankyo Company, Limited,Orphan Disease Treatment Institute Co., Ltd.
- Current Assignee: Masafumi Matsuo,Yasuhiro Takeshima,Daiichi Sankyo Company, Limited,Orphan Disease Treatment Institute Co., Ltd.
- Current Assignee Address: JP Kobe-shi JP Kobe-shi JP Tokyo JP Tokyo
- Agency: Oblon, Spivak, McClelland, Maier & Neustadt, L.L.P.
- Priority: JP2002-340857 20021125; JP2003-204381 20030731
- Main IPC: C07H21/04
- IPC: C07H21/04 ; C07H21/02
Abstract:
Oligonucleotides having a nucleotide sequence complementary to nucleotide numbers such as 2571-2607, 2578-2592, 2571-2592, 2573-2592, 2578-2596, 2578-2601 or 2575-2592 of the dystrophin cDNA (Gene Bank accession No. NM_004006.1) and therapeutic agents for muscular dystrophy comprising such oligonucleotides.
Public/Granted literature
- US20110046360A1 ENA NUCLEIC ACID DRUGS MODIFYING SPLICING IN mRNA PRECURSOR Public/Granted day:2011-02-24
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