Invention Grant
US08624036B2 2-aryl-propionic acids and derivatives and pharmaceutical compositions containing them
有权
2-芳基 - 丙酸及其衍生物和含有它们的药物组合物
- Patent Title: 2-aryl-propionic acids and derivatives and pharmaceutical compositions containing them
- Patent Title (中): 2-芳基 - 丙酸及其衍生物和含有它们的药物组合物
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Application No.: US13063105Application Date: 2009-09-18
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Publication No.: US08624036B2Publication Date: 2014-01-07
- Inventor: Marcello Allegretti , Andrea Aramini , Gianluca Bianchini , Maria Candida Cesta
- Applicant: Marcello Allegretti , Andrea Aramini , Gianluca Bianchini , Maria Candida Cesta
- Applicant Address: IT L'Aquila AQ
- Assignee: Dompe S.p.A.
- Current Assignee: Dompe S.p.A.
- Current Assignee Address: IT L'Aquila AQ
- Agency: Steinfl & Bruno LLP
- Priority: EP08164605 20080918
- International Application: PCT/EP2009/062109 WO 20090918
- International Announcement: WO2010/031835 WO 20100325
- Main IPC: A61K31/421
- IPC: A61K31/421 ; A61K31/426 ; C07D263/48 ; C07D277/42
Abstract:
The present invention relates to (R,S) 2-aryl-propionic acids and derivatives, their single enantiomer (S) and to pharmaceutical compositions containing them, which are used in the prevention and treatment of tissue damage due to the exacerbated recruitment of polymorphonucleated neutrophils (PIvTN leukocytes) at inflammation sites. The present invention provides compounds for use in the treatment of transient cerebral ischemia, bullous pemphigo, rheumatoid arthritis, idiopathic fibrosis, glomerulonephritis and damages caused by ischemia and reperfusion.
Public/Granted literature
- US20110207785A1 2-Aryl-Propionic Acids and Derivatives and Pharmaceutical Compositions Containing Them Public/Granted day:2011-08-25
Information query
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