An image pickup apparatus arranged to derive a change amount of an image B to an image A as combination position information, on the basis of which the image B is combined to the image A by shifting a position of the image B to generate a combined image D and a position of pixel defect information of the image B is changed, and synthesize pixel defect information of the image A and pixel defect information of the image B after the change to generate pixel defect information of the combined image D such that the pixel defect information in which a detection level corresponding to ISO100 is deleted from the pixel defect information of the combined image D and a detection level of pixel defect information of the pixel shown by same addresses is raised.