A method of, at a base station, transmitting spread signals in a wireless communication system includes spreading a plurality of signals using a spreading code with a predetermined spreading factor, multiplexing a plurality of spread signals to construct one or more spread signal groups, mapping the one or more spread signal groups to one or more specific Control Channel Elements (CCEs) set within one or more Orthogonal Frequency Division Multiplexing (OFDM) symbols, and transmitting the spread signals to User Equipments (UEs) through the one or more CCEs.