Systems and methods for distributed antenna system reverse path summation using signal-to-noise ratio optimization are provided. In one embodiment, a method for reverse path summation for a distributed antenna system comprises: normalizing an uplink noise floor for a plurality of remote antenna units of a distributed antenna system, wherein the uplink noise floor is normalized based on a first remote antenna unit having a lowest noise floor of the plurality of remote antenna units; and scaling an uplink output gain of each of the plurality of remote antenna units by a scaling factor, wherein the scaling factor attenuates the uplink output gain based on a composite maximum host peak power for a host unit coupled to the plurality of remote antenna units.