Methods and systems for flexible and repeatable pre-route generation are described. In one embodiment, a routing selection is received. The routing selection is for a path between at least a first cell and a second cell. The first and second cell are associated with a functional description of an integrated circuit. A floorplan associated with the functional description is modified to create a modified floorplan. The modified floorplan has a physical design change relative to the floorplan. A pre-route is automatically generated based on receipt of the routing selection and the modified floorplan. The pre-route is added to a physical design of the chip to create a pre-routed physical design. Additional methods and systems are disclosed.