An internal combustion engine with a kick starter for ensuring layout flexibility of a kick shaft while suppressing an enlargement of the engine. An output shaft is disposed at a position overlapped with a driven pulley from a side view. A power transmission mechanism is disposed between the output shaft and the driven shaft pulley in a crankcase. A kick shaft is disposed at a position below and forward of the driven pulley shaft, which is not overlapped with the driven pulley from the side view. A kick intermediate shaft is disposed between the kick shaft and the crankshaft such that the kick starter is mounted on the crankcase.