Various universal ports for installation into a colon are disclosed. Various embodiments include expandable port bodies that may employ selectively deployable tissue-engaging barbs for securing the port in position within the colon. Some embodiments also employ tissue cutting members that may be deployed to sever the colon. Some embodiments also employ a flexible sleeve that may extend from the port out through the anus to provide a passageway for passing surgical instruments and into and out of the rectum and also for removing severed specimens therefrom.