Invention Grant
- Patent Title: High molecular weight derivatives of vitamin K-dependent polypeptides
- Patent Title (中): 维生素K依赖多肽的高分子量衍生物
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Application No.: US11696579Application Date: 2007-04-04
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Publication No.: US08632771B2Publication Date: 2014-01-21
- Inventor: Gary L. Nelsestuen , Ronald Bach , Matthew Stone , Stephen Barrett Harvey
- Applicant: Gary L. Nelsestuen , Ronald Bach , Matthew Stone , Stephen Barrett Harvey
- Applicant Address: US MN Minneapolis US DC Washington
- Assignee: Regents of the University of Minnesota,The United States of America as represented by Department of Veterens Affairs
- Current Assignee: Regents of the University of Minnesota,The United States of America as represented by Department of Veterens Affairs
- Current Assignee Address: US MN Minneapolis US DC Washington
- Agency: Fish & Richardson P.C.
- Main IPC: A61K38/48
- IPC: A61K38/48
Abstract:
Modifications of vitamin K-dependent polypeptides that lead to enhanced protein function on a weight or molar basis and/or increase of protein lifetime in the circulation are described. Both objectives are important for using vitamin K-dependent polypeptides for pro- and anti-coagulation therapies, as well as for other uses in the circulation.
Public/Granted literature
- US20080004221A1 High Molecular Weight Derivatives of Vitamin K-Dependent Polypeptides Public/Granted day:2008-01-03
Information query
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