Invention Grant
US08632962B2 PLKS as modifiers of the beta catenin pathway and methods of use
失效
PLKS作为β连环蛋白途径的修饰剂和使用方法
- Patent Title: PLKS as modifiers of the beta catenin pathway and methods of use
- Patent Title (中): PLKS作为β连环蛋白途径的修饰剂和使用方法
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Application No.: US10580131Application Date: 2004-11-23
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Publication No.: US08632962B2Publication Date: 2014-01-21
- Inventor: Helen Francis-Lang , Christopher G. Winter , Richard Benn Abegania Ventura , Lynn Margaret Bjerke , Timothy S. Heuer
- Applicant: Helen Francis-Lang , Christopher G. Winter , Richard Benn Abegania Ventura , Lynn Margaret Bjerke , Timothy S. Heuer
- Applicant Address: US CA South San Francisco
- Assignee: Exelixis, Inc.
- Current Assignee: Exelixis, Inc.
- Current Assignee Address: US CA South San Francisco
- Agency: McDonnell Boehnen Hulbert & Berghoff LLP
- International Application: PCT/US2004/039549 WO 20041123
- International Announcement: WO2005/051319 WO 20050609
- Main IPC: C12Q1/00
- IPC: C12Q1/00 ; C12Q1/68 ; G01N33/53
Abstract:
Human PLK genes are identified as modulators of the beta catenin pathway, and thus are therapeutic targets for disorders associated with defective beta catenin function. Methods for identifying modulators of beta catenin, comprising screening for agents that modulate the activity of PLK are provided.
Public/Granted literature
- US20080274122A1 Plks as Modifiers of the Beta Catenin Pathway and Methods of Use Public/Granted day:2008-11-06
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