Invention Grant
- Patent Title: Biomarkers for pancreatic cancer and diagnostic methods
- Patent Title (中): 胰腺癌生物标志物和诊断方法
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Application No.: US12951718Application Date: 2010-11-22
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Publication No.: US08632983B2Publication Date: 2014-01-21
- Inventor: Brian B. Haab , Tingting Yue , Randall E. Brand
- Applicant: Brian B. Haab , Tingting Yue , Randall E. Brand
- Applicant Address: US MI Grand Rapids US PA Pittsburgh
- Assignee: Van Andel Research Institute,University of Pittsburgh - Of The Commonwealth System of Higher Education
- Current Assignee: Van Andel Research Institute,University of Pittsburgh - Of The Commonwealth System of Higher Education
- Current Assignee Address: US MI Grand Rapids US PA Pittsburgh
- Agency: Honigman Miller Schwartz and Cohn LLP
- Agent Douglas H. Siegel; Jonathan P. O'Brien
- Main IPC: G01N33/53
- IPC: G01N33/53 ; C12Q1/00
Abstract:
Methods and related kits for differentiating pancreatic cancer from a benign pancreatic disease. The method includes assaying a patient biological sample for a total level of CA 19-9 antigen and for a glycan level in specific mucin(s), and comparing the total level of CA 19-9 antigen and the glycan level in the specific mucin(s) to statistically validated thresholds, wherein a different level of total CA 19-9 antigen in the patient biological sample as compared to a statistically validated threshold and a different level of glycan level in the specific mucin(s) as compared to statistically validated thresholds indicate pancreatic cancer in the patient rather than a benign pancreatic disease.
Public/Granted literature
- US20110257029A1 BIOMARKERS FOR PANCREATIC CANCER AND DIAGNOSTIC METHODS Public/Granted day:2011-10-20
Information query
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