Invention Grant
- Patent Title: SiRNA targeting histamine receptor H1
- Patent Title (中): 靶向组胺受体H1的SiRNA
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Application No.: US13136780Application Date: 2011-08-10
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Publication No.: US08633306B2Publication Date: 2014-01-21
- Inventor: Anastasia Khvorova , Angela Reynolds , Devin Leake , William Marshall , Steven Read , Stephen Scaringe
- Applicant: Anastasia Khvorova , Angela Reynolds , Devin Leake , William Marshall , Steven Read , Stephen Scaringe
- Applicant Address: US CO Lafayette
- Assignee: Thermo Fisher Scientific Biosciences Inc.
- Current Assignee: Thermo Fisher Scientific Biosciences Inc.
- Current Assignee Address: US CO Lafayette
- Agency: Dorf & Nelson LLP
- Agent Scott D. Locke, Esq.
- Main IPC: C07H21/02
- IPC: C07H21/02 ; C07H21/04 ; A61K31/70 ; C12Q1/68
Abstract:
Efficient sequence specific gene silencing is possible through the use of siRNA technology. By selecting particular siRNAs by rational design, one can maximize the generation of an effective gene silencing reagent, as well as methods for silencing genes. Methods, compositions, and kits generated through rational design of siRNAs are disclosed.
Public/Granted literature
- US20110319296A1 siRNA targeting histamine receptor H1 Public/Granted day:2011-12-29
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