Described embodiments include a system, method, and program product. A described system includes a circuit that extracts a human-perceivable feature included in each medical skin image of a plurality of medical skin images. Each medical skin image includes a respective portion of a region of interest of a surface of the skin of the individual human, and was acquired by a handheld device. A circuit determines a substantial correspondence between (x) a human-perceivable feature included in a border region segment of a selected medical skin image and (y) a human-perceivable feature included in each medical skin image of the plurality of medical skin images other than the selected medical skin image. A circuit gathers the determined substantial correspondences. A circuit outputs informational data indicative of a possible non-imaged portion of the region of interest of the skin of the individual human adjacent to the selected medical skin image.