The present invention is directed generally to a system and method which employ a compressed gas-driven device with a passive thermodynamic composition. Certain embodiments provide a compressed gas-driven (e.g., CO2-driven) device implementation that includes a passive thermodynamic composition which allows for extended use of the device without freezing and without requiring a persistently-maintained, active (e.g., electrically-powered) heating. Further, certain embodiments provide a compressed gas-driven (e.g., CO2-driven) device implementation that includes a passive thermodynamic composition which allows for extended use of the device without freezing and without requiring an ignition heat source (e.g., electrically-powered or pyrotechnic as generator) for heating the device. In one embodiment, a CO2-driven sanitizing device is provided for dispensing a sanitizing solution, wherein a passive thermodynamic composition is employed for enabling substantially-continuous use of the sanitizing device for an extended time without requiring an on-board active heater.