Invention Grant
US08636983B2 Aminoglycoside and fosfomycin combination for treatment of ventilator associated pneumonia (VAP) and ventilator associated tracheal (VAT) bronchitis 失效
氨基糖苷和磷霉素组合治疗呼吸机相关性肺炎(VAP)和呼吸机相关气管(VAT)支气管炎

  • Patent Title: Aminoglycoside and fosfomycin combination for treatment of ventilator associated pneumonia (VAP) and ventilator associated tracheal (VAT) bronchitis
  • Patent Title (中): 氨基糖苷和磷霉素组合治疗呼吸机相关性肺炎(VAP)和呼吸机相关气管(VAT)支气管炎
  • Application No.: US13941000
    Application Date: 2013-07-12
  • Publication No.: US08636983B2
    Publication Date: 2014-01-28
  • Inventor: Alan Bruce Montgomery
  • Applicant: Cardeas Pharma Inc.
  • Applicant Address: US WA Seattle
  • Assignee: Cardeas Pharma Inc.
  • Current Assignee: Cardeas Pharma Inc.
  • Current Assignee Address: US WA Seattle
  • Agent Kurt T. Mulville
  • Main IPC: A61K9/14
  • IPC: A61K9/14 A61K9/12
Aminoglycoside and fosfomycin combination for treatment of ventilator associated pneumonia (VAP) and ventilator associated tracheal (VAT) bronchitis
Abstract:
The present invention is antibiotic compositions, ventilator-based systems and methods relating to ventilator-associated pneumonia (VAP) and ventilator-associated tracheal (VAT) bronchitis. Antibiotic combinations of fosfomycin and an aminoglycoside, preferably amikacin, are administered via an inline nebulizer within the airway of the ventilator. Humidified conditions create an improved aerosol mist to treat VAP and VAT.
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