Invention Grant
- Patent Title: Anti c-Met antibodies
- Patent Title (中): 抗c-Met抗体
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Application No.: US13288566Application Date: 2011-11-03
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Publication No.: US08637027B2Publication Date: 2014-01-28
- Inventor: Anna Hultberg , Michael Saunders , Johannes De Haard , Els Festjens , Natalie De Jonge , Paolo Michieli , Cristina Basilico , Torsten Dreier
- Applicant: Anna Hultberg , Michael Saunders , Johannes De Haard , Els Festjens , Natalie De Jonge , Paolo Michieli , Cristina Basilico , Torsten Dreier
- Applicant Address: NL Breda
- Assignee: arGEN-X B.V.
- Current Assignee: arGEN-X B.V.
- Current Assignee Address: NL Breda
- Agency: Lathrop & Gage LLP
- Agent James H. Velema, Esq.; Andrew T. Wilkins, Esq.
- Main IPC: A61K39/395
- IPC: A61K39/395 ; C07K16/28 ; C07K16/32

Abstract:
The present invention relates to antibodies that specifically bind to the human c-Met receptor protein and that act as strict antagonists of hepatocyte growth factor (HGF)-mediated activation of the c-Met receptor and also inhibit HGF-independent activation of the human c-Met protein.
Public/Granted literature
- US20120148607A1 ANTI C-MET ANTIBODIES Public/Granted day:2012-06-14
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