Invention Grant
- Patent Title: Method for the detection of EGFR mutations in blood samples
- Patent Title (中): 检测血液样品中EGFR突变的方法
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Application No.: US12374307Application Date: 2007-07-20
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Publication No.: US08637245B2Publication Date: 2014-01-28
- Inventor: Rafael Rosell Costa , Miguel Taron Roca
- Applicant: Rafael Rosell Costa , Miguel Taron Roca
- Applicant Address: ES Barcelona
- Assignee: Pangea Biotech, S.A.
- Current Assignee: Pangea Biotech, S.A.
- Current Assignee Address: ES Barcelona
- Agency: Hultquist IP PLLC
- Agent Steven J. Hultquist; Mary B. Grant
- Priority: EP06117551 20060720
- International Application: PCT/EP2007/057510 WO 20070720
- International Announcement: WO2008/009740 WO 20080124
- Main IPC: C12Q1/68
- IPC: C12Q1/68 ; C12P19/34 ; C07H21/04

Abstract:
The present invention refers to the detection of EGFR mutations in a blood (serum/plasma) sample from a subject. The method comprises: (i) obtaining the DNA from said sample; (ii) amplifying the nucleic acid sequence corresponding to a specific region of the EGFR gene by means of PCR using a Protein-Nucleic Acid probe; 10 and (iii) detecting said mutation.
Public/Granted literature
- US20100009360A1 METHOD FOR THE DETECTION OF EGFR MUTATIONS IN BLOOD SAMPLES Public/Granted day:2010-01-14
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