Invention Grant
- Patent Title: Methods of detecting target nucleic acids
- Patent Title (中): 检测靶核酸的方法
-
Application No.: US13590794Application Date: 2012-08-21
-
Publication No.: US08637247B2Publication Date: 2014-01-28
- Inventor: Muhammad Sharaf , Timothy Woudenberg , Khairuzzaman Bashar Mullah
- Applicant: Muhammad Sharaf , Timothy Woudenberg , Khairuzzaman Bashar Mullah
- Applicant Address: US CA Carlsbad
- Assignee: Applied Biosystems, LLC
- Current Assignee: Applied Biosystems, LLC
- Current Assignee Address: US CA Carlsbad
- Main IPC: C12Q1/68
- IPC: C12Q1/68

Abstract:
The present disclosure relates to methods of identifying target nucleic acids by using coded molecules and its analysis by translocation through a nanopore. Generally, coded molecules are subject to a target polynucleotide dependent modification. The modified coded molecule is detected by isolating the modified coded molecules from the unmodified coded molecules prior to analysis through the nanopore or by detecting a change in the signal pattern of the coded molecule when analyzed through the nanopore.
Public/Granted literature
- US20120316083A1 Methods of Detecting Target Nucleic Acids Public/Granted day:2012-12-13
Information query