Invention Grant
US08637285B2 Generation of pulsating pressure waves, E.G. for cell lysis 有权
脉动压力波的产生,E.G. 用于细胞裂解

  • Patent Title: Generation of pulsating pressure waves, E.G. for cell lysis
  • Patent Title (中): 脉动压力波的产生,E.G. 用于细胞裂解
  • Application No.: US11722875
    Application Date: 2005-12-23
  • Publication No.: US08637285B2
    Publication Date: 2014-01-28
  • Inventor: Tomas Ussing
  • Applicant: Tomas Ussing
  • Applicant Address: DK Taastrup
  • Assignee: Memsflow ApS
  • Current Assignee: Memsflow ApS
  • Current Assignee Address: DK Taastrup
  • Agency: Foley & Lardner LLP
  • Priority: DKPA200402034 20041231; DKPA200500484 20050406
  • International Application: PCT/DK2005/000825 WO 20051223
  • International Announcement: WO2006/069577 WO 20060706
  • Main IPC: C12Q1/00
  • IPC: C12Q1/00 C12N13/00
Generation of pulsating pressure waves, E.G. for cell lysis
Abstract:
The present invention relates to a method by which a controlled source of heat (preferably a laser 3) generates a pulsating vapor bubble 4 in an enclosed liquid. The pulsating rate (the frequency) is preferably in the ultrasonic region, whereby cavitation occurs in the liquid. The cavitation effect will cause disruption of suspended components such as cells or bacterial spores. The ultrasonic disruption of cellular components is known as lysing by sonication.
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