Invention Grant
- Patent Title: Eukaryotic cell display systems
- Patent Title (中): 真核细胞显示系统
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Application No.: US12291889Application Date: 2008-11-14
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Publication No.: US08637435B2Publication Date: 2014-01-28
- Inventor: Kevin Caili Wang , Peter Peizhi Luo , Pingyu Zhong , Jian Wang
- Applicant: Kevin Caili Wang , Peter Peizhi Luo , Pingyu Zhong , Jian Wang
- Applicant Address: US NJ Rahway
- Assignee: Merck Sharp & Dohme Corp.
- Current Assignee: Merck Sharp & Dohme Corp.
- Current Assignee Address: US NJ Rahway
- Agent Patricia L. Chisholm; Immac J. Thampoe
- Main IPC: C40B40/02
- IPC: C40B40/02 ; C40B50/06

Abstract:
The present invention provides expression vectors and helper display vectors which can be used in various combinations as vector sets for display of polypeptides on the outer surface of eukaryotic host cells. The expression vector of the invention can be used alone for soluble expression without having to change or reengineer the display vectors. The display systems of the invention are particularly useful for displaying a genetically diverse repertoire or library of polypeptides on the surface of yeast cells, and mammalian cells.
Public/Granted literature
- US20090163379A1 Eukaryotic cell display systems Public/Granted day:2009-06-25
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