Invention Grant
- Patent Title: Processes for preparing protease inhibitors of hepatitis C virus
- Patent Title (中): 制备丙型肝炎病毒蛋白酶抑制剂的方法
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Application No.: US13392168Application Date: 2010-08-26
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Publication No.: US08637449B2Publication Date: 2014-01-28
- Inventor: Zhiguo Jake Song , Yaling Wang , David M. Tellers , Laura M. Artino , David R. Lieberman
- Applicant: Zhiguo Jake Song , Yaling Wang , David M. Tellers , Laura M. Artino , David R. Lieberman
- Applicant Address: US NJ Rahway
- Assignee: Merck Sharp & Dohme Corp.
- Current Assignee: Merck Sharp & Dohme Corp.
- Current Assignee Address: US NJ Rahway
- Agent Henry P. Wu; Sheldon O. Heber
- International Application: PCT/US2010/046725 WO 20100826
- International Announcement: WO2011/025849 WO 20110303
- Main IPC: A61K38/00
- IPC: A61K38/00
Abstract:
The present invention relates to synthetic processes useful in the preparation of macrocyclic compounds of Formula (I) that are useful as inhibitors of the hepatitis C virus NS3 protease and have application in the treatment of conditions caused by the hepatitis C virus. The present invention also encompasses intermediates useful in the disclosed synthetic processes and the methods of their preparation.
Public/Granted literature
- US20120232247A1 PROCESSES FOR PREPARING PROTEASE INHIBITORS OF HEPATITIS C VIRUS Public/Granted day:2012-09-13
Information query
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