Invention Grant
US08637459B2 Enhancing a population of insulin releasing cells using GFR-A1 agonists
有权
使用GFR-A1激动剂增强胰岛素释放细胞群体
- Patent Title: Enhancing a population of insulin releasing cells using GFR-A1 agonists
- Patent Title (中): 使用GFR-A1激动剂增强胰岛素释放细胞群体
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Application No.: US11936413Application Date: 2007-11-07
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Publication No.: US08637459B2Publication Date: 2014-01-28
- Inventor: Shanthi Srinivasan
- Applicant: Shanthi Srinivasan
- Applicant Address: US GA Atlanta
- Assignee: Emory University
- Current Assignee: Emory University
- Current Assignee Address: US GA Atlanta
- Agency: Emory Patent Group
- Agent James C. Mason; Susanne Hollinger
- Main IPC: A61K38/00
- IPC: A61K38/00
Abstract:
Provided herein are pharmaceutical and transplant compositions and methods related to the treatment and prevention of diabetes. More specifically, the compositions and methods are related to activation of glial derived neurotrophic factor (GDNF) receptors or overexpression of the GFR-α1/c-Ret receptor complex in insulin secreting cells so as to promote cell survival and proliferation.
Public/Granted literature
- US20080187522A1 ENHANCING A POPULATION OF INSULIN RELEASING CELLS USING GFR-A1 AGONISTS Public/Granted day:2008-08-07
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