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US08637465B2 Fibroblast growth factor receptor-derived peptides binding to NCAM 失效
成纤维细胞生长因子受体衍生的肽结合NCAM

Fibroblast growth factor receptor-derived peptides binding to NCAM
Abstract:
The present invention relates to the use of peptides that are capable of binding to, and modulating the activity of NCAM. The peptides are peptide fragments of FGFRs. They are derived from two distinct binding sites for binding of the immunoglobulin-like module 2 of FGFR to NCAM F3 modules 1-2. The invention further relates to use of said peptides for the production of a medicament for the treatment of different pathological conditions, wherein NCAM and/or FGFRs play a prominent role.
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