Invention Grant
US08637501B2 Azinone-substituted azepino[b]indole and pyrido-pyrrolo-azepine MCH-1 antagonists, methods of making, and use thereof
失效
氮杂酮取代的氮杂环庚烯并[b]吲哚和吡啶并吡咯并吖庚因MCH-1拮抗剂，其制备方法和用途
![Azinone-substituted azepino[b]indole and pyrido-pyrrolo-azepine MCH-1 antagonists, methods of making, and use thereof](/docs/US/2014-01-28/US08637501B2/abs.jpg.600x600.jpg)
- Patent Title: Azinone-substituted azepino[b]indole and pyrido-pyrrolo-azepine MCH-1 antagonists, methods of making, and use thereof
- Patent Title (中): 氮杂酮取代的氮杂环庚烯并[b]吲哚和吡啶并吡咯并吖庚因MCH-1拮抗剂，其制备方法和用途
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Application No.: US12828807Application Date: 2010-07-01
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Publication No.: US08637501B2Publication Date: 2014-01-28
- Inventor: Peter R. Guzzo , Matthew David Surman , James Francis Grabowski, Jr. , Emily Elizabeth Freeman
- Applicant: Peter R. Guzzo , Matthew David Surman , James Francis Grabowski, Jr. , Emily Elizabeth Freeman
- Applicant Address: US NY Albany
- Assignee: Albany Molecular Research, Inc.
- Current Assignee: Albany Molecular Research, Inc.
- Current Assignee Address: US NY Albany
- Agency: LeClairRyan, a Professional Corporation
- Main IPC: A61P3/04
- IPC: A61P3/04 ; A61P25/00 ; A61K31/55 ; C07D487/02
![Azinone-substituted azepino[b]indole and pyrido-pyrrolo-azepine MCH-1 antagonists, methods of making, and use thereof](/abs-image/US/2014/01/28/US08637501B2/abs.jpg.150x150.jpg)
Abstract:
Novel MCH-1 receptor antagonists are disclosed. These compounds are used in the treatment of various disorders, including obesity, anxiety, depression, non-alcoholic fatty liver disease, and psychiatric disorders. Methods of making these compounds are also described in the present invention.
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