Invention Grant
- Patent Title: Sulfur-containing heterocyclic derivative having beta secretase inhibitory activity
- Patent Title (中): 含有β分泌酶抑制活性的含硫杂环衍生物
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Application No.: US12997802Application Date: 2009-06-11
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Publication No.: US08637504B2Publication Date: 2014-01-28
- Inventor: Akihiro Hori , Terukazu Kato
- Applicant: Akihiro Hori , Terukazu Kato
- Applicant Address: JP Osaka
- Assignee: Shionogi & Co., Ltd.
- Current Assignee: Shionogi & Co., Ltd.
- Current Assignee Address: JP Osaka
- Agency: Hamre, Schumann, Mueller & Larson, P.C.
- Priority: JP2008-154990 20080613; JP2008-271689 20081022; JP2009-103616 20090422
- International Application: PCT/JP2009/060696 WO 20090611
- International Announcement: WO2009/151098 WO 20091217
- Main IPC: A61K31/535
- IPC: A61K31/535 ; A61K31/541 ; C07D279/00 ; C07D265/00

Abstract:
The following compound is provided as an agent for treating a disease induced by production, secretion and/or deposition of amyloid β protein, for example, a compound represented by the formula (I): wherein ring A is an optionally substituted carbocyclic group or an optionally substituted heterocyclic group, R1 is optionally substituted lower alkyl or the like, R2a and R2b are each independently hydrogen, optionally substituted lower alkyl or the like, R3a and R3c are each independently hydrogen, halogen, hydroxy, optionally substituted lower alkyl or the like, or a pharmaceutically acceptable salt thereof, or a solvate thereof.
Public/Granted literature
- US20110190279A1 SULFUR-CONTAINING HETEROCYCLIC DERIVATIVE HAVING BETA SECRETASE INHIBITORY ACTIVITY Public/Granted day:2011-08-04
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