Invention Grant
US08637527B2 Imidazolo-, oxazolo-, and thiazolopyrimidine modulators of TRPV1
有权
TRPV1的咪唑并，唑嗪和噻唑并嘧啶调节剂
- Patent Title: Imidazolo-, oxazolo-, and thiazolopyrimidine modulators of TRPV1
- Patent Title (中): TRPV1的咪唑并，唑嗪和噻唑并嘧啶调节剂
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Application No.: US13611936Application Date: 2012-09-12
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Publication No.: US08637527B2Publication Date: 2014-01-28
- Inventor: Bryan James Branstetter , J. Guy Breitenbucher , Alec D. Lebsack , Jing Liu , Jason C Rech , Wei Xiao
- Applicant: Bryan James Branstetter , J. Guy Breitenbucher , Alec D. Lebsack , Jing Liu , Jason C Rech , Wei Xiao
- Applicant Address: BE Beerse
- Assignee: Janssen Pharmaceutica NV
- Current Assignee: Janssen Pharmaceutica NV
- Current Assignee Address: BE Beerse
- Agent Michael J. Atkins
- Main IPC: C07D487/04
- IPC: C07D487/04 ; A61K31/519 ; A61K31/397 ; A61K31/496 ; A61K31/497 ; A61P25/02 ; A61P29/00 ; A61P19/02 ; C07D473/34 ; C07D473/28 ; C07D473/32 ; A61K31/52
Abstract:
Certain TRPV1-modulating imidazolo-, oxazolo-, and thiazolopyrimdine compounds are described. The compounds may be used in pharmaceutical compositions and methods for treating disease states, disorders, and conditions mediated by TRPV1 activity, such as pain, arthritis, itch, cough, asthma, or inflammatory bowel disease.
Public/Granted literature
- US20130005687A1 IMIDAZOLO-, OXAZOLO-, AND THIAZOLOPYRIMIDINE MODULATORS OF TRPV1 Public/Granted day:2013-01-03
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