Invention Grant
US08637536B2 Pyrimidinone compounds for use in the treatment of diseases or conditions mediated by Lp-PLA2
有权
用于治疗由Lp-PLA2介导的疾病或病症的嘧啶酮化合物
- Patent Title: Pyrimidinone compounds for use in the treatment of diseases or conditions mediated by Lp-PLA2
- Patent Title (中): 用于治疗由Lp-PLA2介导的疾病或病症的嘧啶酮化合物
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Application No.: US13310818Application Date: 2011-12-05
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Publication No.: US08637536B2Publication Date: 2014-01-28
- Inventor: Yun Jin , Zehong Wan , Qing Zhang
- Applicant: Yun Jin , Zehong Wan , Qing Zhang
- Applicant Address: GB Brentford, Middlesex
- Assignee: Glaxo Group Limited
- Current Assignee: Glaxo Group Limited
- Current Assignee Address: GB Brentford, Middlesex
- Agent Fang Qian; James Kellerman
- Priority: WOPCT/CN2010/079465 20101206
- Main IPC: C07D239/36
- IPC: C07D239/36 ; A61K31/505
Abstract:
The present invention relates to novel compounds that inhibit Lp-PLA2 activity, processes for their preparation, to compositions containing them and to their use in the treatment of diseases associated with the activity of Lp-PLA2, for example atherosclerosis, Alzheimer's disease, and/or diabetic macular edema.
Public/Granted literature
- US20120142717A1 COMPOUNDS Public/Granted day:2012-06-07
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