Invention Grant
US08637539B2 Remedies for neuropathic pain and model animals of neuropathic pain
有权
神经性疼痛和模型动物的神经性疼痛的补救措施
- Patent Title: Remedies for neuropathic pain and model animals of neuropathic pain
- Patent Title (中): 神经性疼痛和模型动物的神经性疼痛的补救措施
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Application No.: US11206489Application Date: 2005-08-18
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Publication No.: US08637539B2Publication Date: 2014-01-28
- Inventor: Hiroshi Nagase , Takashi Endo , Kuniaki Kawamura , Toshiaki Tanaka , Tomohiko Suzuki , Tsutomu Suzuki , Yasushi Kuraishi , Kimiyasu Shiraki
- Applicant: Hiroshi Nagase , Takashi Endo , Kuniaki Kawamura , Toshiaki Tanaka , Tomohiko Suzuki , Tsutomu Suzuki , Yasushi Kuraishi , Kimiyasu Shiraki
- Applicant Address: JP
- Assignee: Toray Industries, Inc.
- Current Assignee: Toray Industries, Inc.
- Current Assignee Address: JP
- Agency: DLA Piper LLP (US)
- Priority: JP11/236778 19990824
- Main IPC: A01N43/42
- IPC: A01N43/42 ; A61K31/44
Abstract:
The present invention relates to a therapeutic agent for neuropathic pain containing, as an active ingredient, a compound represented by general formula (I) or a pharmacologically acceptable acid addition salt thereof: (wherein R1, R2, R3, R4, R5, R6, R7, R8, A, and B have the same definitions as those described in the specification), and an animal model produced by administering (+)-4a-(3-hydroxyphenyl)-2-methyl-1,2,3,4,4a,5,12,12a-octohydro-trans-quinolino[2,3-g]isoquinoline. The present invention makes it possible to perform drug treatment for neuropathic pain. The therapeutic effect of a compound against neuropathic pain can also be evaluated.
Public/Granted literature
- US20060094741A1 Remedies for neuropathic pain and model animals of neuropathic pain Public/Granted day:2006-05-04
Information query
IPC分类:
