Invention Grant
- Patent Title: Linked Myc-max small molecule inhibitors
- Patent Title (中): 连接的Myc-max小分子抑制剂
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Application No.: US13144674Application Date: 2010-01-15
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Publication No.: US08637556B2Publication Date: 2014-01-28
- Inventor: Steven J. Metallo , Edward V. Prochownik , Ariele Viacava Follis
- Applicant: Steven J. Metallo , Edward V. Prochownik , Ariele Viacava Follis
- Applicant Address: US PA Pittsburgh US DC Washington
- Assignee: University of Pittsburgh—Of the Commonwealth System of Higher Education,Georgetown University
- Current Assignee: University of Pittsburgh—Of the Commonwealth System of Higher Education,Georgetown University
- Current Assignee Address: US PA Pittsburgh US DC Washington
- Agency: Klarquist Sparkman LLP.
- International Application: PCT/US2010/021183 WO 20100115
- International Announcement: WO2010/083404 WO 20100722
- Main IPC: A61K31/427
- IPC: A61K31/427 ; A61K31/4245 ; C07D277/04 ; C07D413/02
Abstract:
Provided herein are compounds and compositions for interfering with the association of Myc and Max. These compounds and compositions are useful in methods for inhibiting growth or proliferation of a cell. Methods of inhibiting growth or proliferation of a cell comprise contacting the cell with an amount of a compound that interferes with Myc and Max association effective to inhibit growth or proliferation of the cell.
Public/Granted literature
- US20120015989A1 LINKED MYC-MAX SMALL MOLECULE INHIBITORS Public/Granted day:2012-01-19
Information query
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