Invention Grant
- Patent Title: Thiazolidinedione derivative and use thereof
- Patent Title (中): 噻唑烷二酮衍生物及其用途
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Application No.: US13142924Application Date: 2009-12-30
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Publication No.: US08637558B2Publication Date: 2014-01-28
- Inventor: Hoon Cho , Ying Wu , Cheol-Hee Choi
- Applicant: Hoon Cho , Ying Wu , Cheol-Hee Choi
- Applicant Address: KR Gwangju
- Assignee: Industry-Academic Cooperation Foundation, Chosun University
- Current Assignee: Industry-Academic Cooperation Foundation, Chosun University
- Current Assignee Address: KR Gwangju
- Agency: JHK Law
- Agent Joseph Hyosuk Kim
- Priority: KR10-2008-0136921 20081230; KR10-2009-0055326 20090622
- International Application: PCT/KR2009/007995 WO 20091230
- International Announcement: WO2010/077101 WO 20100708
- Main IPC: A61K31/426
- IPC: A61K31/426 ; C07D277/34
Abstract:
The present invention relates to novel thiazolidinedione derivatives expressed by the following formula (I) and the uses thereof. More specifically, the present invention relates to novel thiazolidinedione derivatives expressed by the following formula (I) and a pharmaceutical composition comprising the same. The novel thiazolidinedione derivatives of formula (I) according to the present invention can be effectively used for the prevention or treatment of cardiovascular disease, gastrointestinal disease and renal disease by inhibiting the activity of 15-hydroxyprostaglandin dehydrogenase (15-PGDH) that decomposes prostaglandins as well as useful for the prevention of hair loss and the stimulation of hair growth, and osteogenic stimulation and wound healing.
Public/Granted literature
- US20110269954A1 NOVEL THIAZOLIDINEDIONE DERIVATIVE AND USE THEREOF Public/Granted day:2011-11-03
Information query
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