Invention Grant
US08637560B2 Imidazolidinone compounds, methods to inhibit deubiquitination and methods of treatment
有权
咪唑啉酮化合物，抑制去泛素化的方法和治疗方法
- Patent Title: Imidazolidinone compounds, methods to inhibit deubiquitination and methods of treatment
- Patent Title (中): 咪唑啉酮化合物，抑制去泛素化的方法和治疗方法
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Application No.: US12669361Application Date: 2008-07-18
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Publication No.: US08637560B2Publication Date: 2014-01-28
- Inventor: William Trenkle , Adrian Wiestner , Qiuyan Wang , Yihong Ye , Helena Mora-Jensen
- Applicant: William Trenkle , Adrian Wiestner , Qiuyan Wang , Yihong Ye , Helena Mora-Jensen
- Applicant Address: US DC Washington
- Assignee: The United States of America as Represented by the Secretary of the Department of Health and Human Services
- Current Assignee: The United States of America as Represented by the Secretary of the Department of Health and Human Services
- Current Assignee Address: US DC Washington
- Agency: Cantor Colburn LLP
- International Application: PCT/US2008/008797 WO 20080718
- International Announcement: WO2009/011910 WO 20090122
- Main IPC: A61K31/4166
- IPC: A61K31/4166 ; C07D233/32
Abstract:
The present invention features imidazolidinone compounds and pharmaceutical compositions of imidazolidinone compounds. The compounds of the invention are utilized in methods of treating a deubiquitination-related disorder in a subject and inhibiting p97-associated deubiquitination.
Public/Granted literature
- US20100286091A1 IMIDAZOLIDINONE COMPOUNDS, METHODS TO INHIBIT DEUBIQUITINATION AND METHODS OF TREATMENT Public/Granted day:2010-11-11
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