Invention Grant
US08637645B2 H5 subtype-specific binding proteins useful for H5 avian influenza diagnosis and surveillance
有权
H5亚型特异性结合蛋白可用于H5禽流感诊断和监测
- Patent Title: H5 subtype-specific binding proteins useful for H5 avian influenza diagnosis and surveillance
- Patent Title (中): H5亚型特异性结合蛋白可用于H5禽流感诊断和监测
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Application No.: US13613813Application Date: 2012-09-13
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Publication No.: US08637645B2Publication Date: 2014-01-28
- Inventor: Yuen Fern Ho , Qing Yun Du , Fang He , Jimmy Hwei-Sing Kwang
- Applicant: Yuen Fern Ho , Qing Yun Du , Fang He , Jimmy Hwei-Sing Kwang
- Applicant Address: SG Singapore
- Assignee: Temasek Life Sciences Laboratory Limited
- Current Assignee: Temasek Life Sciences Laboratory Limited
- Current Assignee Address: SG Singapore
- Agency: Rothwell, Figg, Ernst & Manbeck P.C.
- Main IPC: A61K39/395
- IPC: A61K39/395 ; C12Q1/70 ; C07K16/10 ; C12N7/00 ; G01N21/64 ; G01N33/569 ; G01N33/577 ; A61K39/145 ; A61K39/42
Abstract:
The invention provides monoclonal antibodies and related binding proteins that bind specifically to the envelope glycoprotein of H5 subtypes of avian influenza virus (“AIV”). The monoclonal antibodies and related binding proteins are useful for the detection of H5 subtypes of AIV, including the pathogenic H5N1 subtypes. Virus may be detected in formalin preserved, paraffin embedded specimens as well as frozen specimens and biological fluids. Accordingly, the invention provides for the diagnosis and surveillance of dangerous viral infections.
Public/Granted literature
- US20130004944A1 H5 Subtype-Specific Binding Proteins Useful for H5 Avian Influenza Diagnosis and Surveillance Public/Granted day:2013-01-03
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