Invention Grant
US08637665B2 Pyrrolo[2,L-C][L,4]benzodiazepine-benzothiazole or benzoxazole conjugates linked through piperazine moiety and process for the preparation thereof
有权
吡咯并[2，L-C] [L，4]苯并二氮杂 - 苯并噻唑或通过哌嗪部分连接的苯并恶唑共轭物及其制备方法
![Pyrrolo[2,L-C][L,4]benzodiazepine-benzothiazole or benzoxazole conjugates linked through piperazine moiety and process for the preparation thereof](/docs/US/2014-01-28/US08637665B2/abs.jpg.600x600.jpg)
- Patent Title: Pyrrolo[2,L-C][L,4]benzodiazepine-benzothiazole or benzoxazole conjugates linked through piperazine moiety and process for the preparation thereof
- Patent Title (中): 吡咯并[2，L-C] [L，4]苯并二氮杂 - 苯并噻唑或通过哌嗪部分连接的苯并恶唑共轭物及其制备方法
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Application No.: US13525555Application Date: 2012-06-18
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Publication No.: US08637665B2Publication Date: 2014-01-28
- Inventor: Kamal Ahmed , Rajesh V. C. R. N. C. Shetti , K. Srinivasa Reddy , Adla Malla Reddy , Ponnampally Swapna
- Applicant: Kamal Ahmed , Rajesh V. C. R. N. C. Shetti , K. Srinivasa Reddy , Adla Malla Reddy , Ponnampally Swapna
- Applicant Address: IN
- Assignee: Council of Scientific & Industrial Research
- Current Assignee: Council of Scientific & Industrial Research
- Current Assignee Address: IN
- Agency: St. Onge Steward Johnston & Reens LLC
- Priority: IN683/DEL/2010 20100322
- Main IPC: C07D487/04
- IPC: C07D487/04
![Pyrrolo[2,L-C][L,4]benzodiazepine-benzothiazole or benzoxazole conjugates linked through piperazine moiety and process for the preparation thereof](/abs-image/US/2014/01/28/US08637665B2/abs.jpg.150x150.jpg)
Abstract:
A compound of general formula 9, useful as potential antitumor agents against human cancer cell line and a process for the preparation of Pyrrolo[2,1-c] [1,4]benzodiazepine-benzothiazole or benzoxazole conjugates linked through piperazine of general formula 9 wherein: R, R1=H, F, OCF3, Cl, OMe; R2=OCH3 or H; n1 n2=3, 4; x=S or O.
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