Invention Grant
US08637704B2 Polymorphs of N-malonyl-bis(N′-methyl-N′-thiobenzoylhydrazide)
失效
N-丙二酰基 - 双（N'-甲基-N'-硫代苯甲酰基酰肼）的多晶型物
- Patent Title: Polymorphs of N-malonyl-bis(N′-methyl-N′-thiobenzoylhydrazide)
- Patent Title (中): N-丙二酰基 - 双（N'-甲基-N'-硫代苯甲酰基酰肼）的多晶型物
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Application No.: US12745096Application Date: 2008-11-28
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Publication No.: US08637704B2Publication Date: 2014-01-28
- Inventor: Elena Kostik , Lijun Sun , Joanna Dziewiszek , Jun Y. Choi
- Applicant: Elena Kostik , Lijun Sun , Joanna Dziewiszek , Jun Y. Choi
- Applicant Address: US MA Lexington
- Assignee: Synta Pharmaceuticals Corp.
- Current Assignee: Synta Pharmaceuticals Corp.
- Current Assignee Address: US MA Lexington
- Agency: McCarter & English, LLP
- Agent Steven G. Davis
- International Application: PCT/US2008/013204 WO 20081128
- International Announcement: WO2009/073148 WO 20090611
- Main IPC: C07C327/56
- IPC: C07C327/56 ; A61K31/166
Abstract:
At least 70% by weight of Compound 1 is the single crystalline form, Form A, Form C, or Form D, of the compound. A pharmaceutical composition comprises a pharmaceutically acceptable carrier or diluent, and compound 1, wherein at least 70% by weight of the compound is the single crystalline form, Form A, Form C, or Form D, of the compound. A method of treating a subject with cancer comprises administering to the subject an effective amount of compound 1 or the pharmaceutical composition.
Public/Granted literature
- US20110196025A1 Polymorphs of N-Malonyl-Bis(N'-Methyl-N'-Thiobenzoylhydrazide) Public/Granted day:2011-08-11
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