Invention Grant
US08639325B2 Method for low-voltage termination of cardiac arrhythmias by effectively unpinning anatomical reentries
有权
通过有效拔除解剖学重新进行的低电压终止心律失常的方法
- Patent Title: Method for low-voltage termination of cardiac arrhythmias by effectively unpinning anatomical reentries
- Patent Title (中): 通过有效拔除解剖学重新进行的低电压终止心律失常的方法
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Application No.: US13464537Application Date: 2012-05-04
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Publication No.: US08639325B2Publication Date: 2014-01-28
- Inventor: Igor R. Efimov , Valentin I. Krinski , Vladimir P. Nikolski
- Applicant: Igor R. Efimov , Valentin I. Krinski , Vladimir P. Nikolski
- Applicant Address: US MO St. Louis
- Assignee: Washington University
- Current Assignee: Washington University
- Current Assignee Address: US MO St. Louis
- Agency: Patterson Thuente Pedersen, P.A.
- Main IPC: A61N1/00
- IPC: A61N1/00

Abstract:
A method for extinguishing a cardiac arrhythmia utilizes destructive interference of the passing of the reentry wave tip of an anatomical reentry through a depolarized region created by a relatively low voltage electric field in such a way as to effectively unpin the anatomical reentry. Preferably, the relatively low voltage electric field is defined by at least one unpinning shock(s) that are lower than an expected lower limit of vulnerability as established, for example, by a defibrillation threshold test. By understanding the physics of the electric field distribution between cardiac cells, the method permits the delivery of an electric field sufficient to unpin the core of the anatomical reentry, whether the precise or estimated location of the reentry is known or unknown and without the risk of inducting ventricular fibrillation. A number of embodiments for performing the method are disclosed.
Public/Granted literature
- US20130013012A1 METHOD FOR LOW-VOLTAGE TERMINATION OF CARDIAC ARRHYTHMIAS BY EFFECTIVELY UNPINNING ANATOMICAL REENTRIES Public/Granted day:2013-01-10
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