Various embodiments of a system, method, and memory-medium provide for configuration of a programmable waveform that allows for communication with one of a plurality of different target devices. The programmable waveform comprises one or more waveform parameters and one or more waveform lines. The waveform lines may comprise control lines and/or data lines. One or more of the waveform parameters may be set in response to user input, and corresponding signals based on the waveform lines may be generated in order to communicate with a target device selected from a variety of different possible target devices. Waveform parameters may include one or more of: setup time, hold time, lead time, trail time, idle time, clock frequency, clock duty cycle, number of data bits per transmission, number of data lines, pulse width, polarity, and phase.