According to certain example embodiments of this invention, there is provided an apparatus for treatment of a patient with both sleep-disordered breathing and diabetes. A PAP device may be configured to provide a supply of pressurized breathable gas. At least one glycemia sensor also may be provided. A controller may be operable to receive a signal from the at least one glycemia detector and may be further operable to analyze the signal for an indication of a glycemia abnormality (e.g., hypoglycemia, hyperglycemia, diabetic coma, etc.). Optionally, when the signal indicates that the patient is experiencing a diabetic event, an alert may be generated and/or a drug delivery unit may administer an appropriate treatment to the patient.