The invention discloses a camera rotation mechanism and a portable electronic apparatus therewith. The camera rotation mechanism includes a rotatable carrier, a bearing structure, and a rotating mechanism, which are disposed in a casing. The rotatable carrier includes a carrier body and a rotatable shaft connected to the carrier body and bore by the bearing structure. A camera module is disposed on the carrier body such that a lens of the camera module is exposed through a lens hole of the casing. The rotating mechanism is connected to the rotatable shaft and includes a rotation operation part partially exposed through a slot hole of the casing and capable of being rotated to rotate the carrier body through the rotatable shaft. Therefore, a user can use the camera rotation mechanism to adjust the disposition angle of the lens, which solves the impossibility of adjusting a fixed camera in the prior art.