Invention Grant
US08642041B2 Adenylyl cyclase-associated protein (CAP1) and uses thereof as a target for immuno-modulation 有权
腺苷酸环化酶相关蛋白(CAP1)及其用作免疫调节的靶标

  • Patent Title: Adenylyl cyclase-associated protein (CAP1) and uses thereof as a target for immuno-modulation
  • Patent Title (中): 腺苷酸环化酶相关蛋白(CAP1)及其用作免疫调节的靶标
  • Application No.: US13257633
    Application Date: 2010-03-21
  • Publication No.: US08642041B2
    Publication Date: 2014-02-04
  • Inventor: Yaakov NaparstekEli Moallem
  • Applicant: Yaakov NaparstekEli Moallem
  • Applicant Address: IL Jerusalem
  • Assignee: Protab Ltd.
  • Current Assignee: Protab Ltd.
  • Current Assignee Address: IL Jerusalem
  • Agency: Browdy and Neimark, PLLC
  • International Application: PCT/IL2010/000231 WO 20100321
  • International Announcement: WO2010/113148 WO 20101007
  • Main IPC: A61K39/00
  • IPC: A61K39/00
Adenylyl cyclase-associated protein (CAP1) and uses thereof as a target for immuno-modulation
Abstract:
The present invention relates to the use of Adenylyl Cyclase-Associated Protein (CAP1) as a target for immuno-modulation. More specifically, the invention relates to the use of compounds that interact and bind CAP1, specifically, anti-CAP1 antibodies, and/or to CAP1 molecule or any fragments thereof, for the treatment of immune-related disorders by modulation of the Th1/Th2 balance. The invention further provides screening method for immuno-modulatory compounds that interact with CAP1.
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