Invention Grant
US08642294B2 Methods for determining cytosine methylation in DNA and uses thereof
有权
确定DNA中胞嘧啶甲基化的方法及其用途
- Patent Title: Methods for determining cytosine methylation in DNA and uses thereof
- Patent Title (中): 确定DNA中胞嘧啶甲基化的方法及其用途
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Application No.: US12451431Application Date: 2008-05-19
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Publication No.: US08642294B2Publication Date: 2014-02-04
- Inventor: John M. Greally , Eli Hatchwell
- Applicant: John M. Greally , Eli Hatchwell
- Applicant Address: US NY Bronx US NY Albany
- Assignee: Albert Einstein College of Medicine of Yeshiva University,The Research Foundation State University of New York
- Current Assignee: Albert Einstein College of Medicine of Yeshiva University,The Research Foundation State University of New York
- Current Assignee Address: US NY Bronx US NY Albany
- Agency: Amster, Rothstein & Ebenstein LLP
- International Application: PCT/US2008/006387 WO 20080519
- International Announcement: WO2008/156536 WO 20081224
- Main IPC: C12P19/34
- IPC: C12P19/34
Abstract:
Methods are described for determining the pattern of cytosine methylation in a DNA specimen, where the methods involve comparing the amount of DNA fragments generated by a methylation-sensitive restriction enzyme with the amount of DNA fragments generated by a methylation-insensitive isoschizomer of the methylation-sensitive restriction enzyme.
Public/Granted literature
- US20100267021A1 METHODS FOR DETERMINING CYTOSINE METHYLATION IN DNA AND USES THEREOF Public/Granted day:2010-10-21
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