Invention Grant
- Patent Title: Compositions of active Wnt protein
- Patent Title (中): 活性Wnt蛋白的组成
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Application No.: US12480550Application Date: 2009-06-08
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Publication No.: US08642335B2Publication Date: 2014-02-04
- Inventor: Roeland Nusse , Karl H. Willert
- Applicant: Roeland Nusse , Karl H. Willert
- Applicant Address: US CA Palo Alto
- Assignee: The Board of Trustees of the Leland Stanford Junior University
- Current Assignee: The Board of Trustees of the Leland Stanford Junior University
- Current Assignee Address: US CA Palo Alto
- Agency: Bozicevic, Field & Francis LLP
- Agent Pamela J. Sherwood
- Main IPC: C12N5/00
- IPC: C12N5/00 ; C12N5/02
Abstract:
Compositions of purified biologically active Wnt proteins are provided. Wnt proteins are found to be hydrophobic and post-translationally modified by addition of a lipid moiety at a conserved cysteine residue. Methods for isolation of Wnt utilize detergents that maintain the solubility of the modified protein.
Public/Granted literature
- US20090275134A1 COMPOSITIONS OF ACTIVE WNT PROTEIN Public/Granted day:2009-11-05
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