Invention Grant
US08642340B2 Plant cell culture for production of natural products with reduced glucosinolate contamination
失效
用于生产具有降低的硫代葡萄糖苷污染的天然产物的植物细胞培养物
- Patent Title: Plant cell culture for production of natural products with reduced glucosinolate contamination
- Patent Title (中): 用于生产具有降低的硫代葡萄糖苷污染的天然产物的植物细胞培养物
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Application No.: US13140381Application Date: 2009-12-17
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Publication No.: US08642340B2Publication Date: 2014-02-04
- Inventor: Helena V. Mathews , Sung-Yong Yoon , Mylavarapu Venkatramesh
- Applicant: Helena V. Mathews , Sung-Yong Yoon , Mylavarapu Venkatramesh
- Applicant Address: US OR Portland
- Assignee: Dianaplantsciences, Inc.
- Current Assignee: Dianaplantsciences, Inc.
- Current Assignee Address: US OR Portland
- Agency: Workman Nydegger
- International Application: PCT/US2009/068559 WO 20091217
- International Announcement: WO2010/080530 WO 20100715
- Main IPC: C12N5/00
- IPC: C12N5/00

Abstract:
Disclosed are methods for obtaining a natural product preparation with reduced glucosinolate contamination from a plant of Brassicaceae. The methods can include cultivating a plant callus from a plant capable of producing a desired natural product, selecting a callus with reduced glucosinolate production, and cultivating the selected callus in a liquid medium. The method can also include recovering the natural product from the culture. Also disclosed are methods for obtaining cabbage anthocyanin with reduced glucosinolate contamination. The methods can include cultivating a red cabbage plant callus with reduced glucosinolate production in a liquid medium to obtain a suspension culture and cultivating the suspension culture in a medium lacking a nitrogen source. The method can also include recovering the anthocyanin with reduced glucosinolate contamination from the culture. Finally, several specific low-glucosinolate cell lines are described.
Public/Granted literature
- US20110251408A1 PLANT CELL CULTURE FOR PRODUCTION OF NATURAL PRODUCTS WITH REDUCED GLUCOSINOLATE CONTAMINATION Public/Granted day:2011-10-13
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