Invention Grant
- Patent Title: Morpholinone compounds as factor IXa inhibitors
- Patent Title (中): 吗啉酮化合物作为因子IXa抑制剂
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Application No.: US12744736Application Date: 2009-12-03
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Publication No.: US08642582B2Publication Date: 2014-02-04
- Inventor: Hidemitsu Nishida , Fumihiko Saitoh , Tomokazu Hirabayashi , Samuel Chackalamannil , Tin-Yau Chan , Mariappan V. Chelliah , Martin C. Clasby , Michael Dwyer , William J. Greenlee , Yan Xia
- Applicant: Hidemitsu Nishida , Fumihiko Saitoh , Tomokazu Hirabayashi , Samuel Chackalamannil , Tin-Yau Chan , Mariappan V. Chelliah , Martin C. Clasby , Michael Dwyer , William J. Greenlee , Yan Xia
- Applicant Address: US NJ Rahway
- Assignee: Merck Sharp & Dohme Corp.
- Current Assignee: Merck Sharp & Dohme Corp.
- Current Assignee Address: US NJ Rahway
- Agent Nicole M. Beeler; Catherine D. Fitch
- International Application: PCT/US2009/066548 WO 20091203
- International Announcement: WO2010/065717 WO 20100610
- Main IPC: A61K31/535
- IPC: A61K31/535
Abstract:
The present invention provides a compound of Formula (I) as described herein, or a pharmaceutically acceptable salt or a solvate thereof. The present invention also provides pharmaceutical compositions comprising one or more said compounds, and methods for using said compounds for treating or preventing a thromboses, embolisms, hypercoagulability or fibrotic changes.
Public/Granted literature
- US20110059958A1 MORPHOLINONE COMPOUNDS AS FACTOR IXA INHIBITORS Public/Granted day:2011-03-10
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