Invention Grant
- Patent Title: Nicotinic desensitizers and methods of selecting, testing, and using them
- Patent Title (中): 烟碱脱敏剂及其选择，测试和使用方法
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Application No.: US12374172Application Date: 2007-07-18
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Publication No.: US08642612B2Publication Date: 2014-02-04
- Inventor: Yingxian Xiao , Kenneth J. Kellar
- Applicant: Yingxian Xiao , Kenneth J. Kellar
- Applicant Address: US MD Potomac
- Assignee: Potomac Pharmaceuticals, Inc.
- Current Assignee: Potomac Pharmaceuticals, Inc.
- Current Assignee Address: US MD Potomac
- Agency: Cooley LLP
- International Application: PCT/US2007/073814 WO 20070718
- International Announcement: WO2008/011484 WO 20080124
- Main IPC: A01N43/40
- IPC: A01N43/40 ; A61K31/435
Abstract:
The present invention discloses nicotinic desensitizers and methods of selecting, testing, and using them. The present invention provides methods for selecting nicotinic desensitizers from one or more compounds by using receptor, cell, and tissue models; and methods for testing one or more nicotinic desensitizers for their therapeutic utility by using animal models. The present invention also provides compounds of formula (I) and (II) as nicotinic desensitizers. Nicotinic desensitizers of the present invention are useful for the treatment of a wide range of conditions, diseases, and disorders.
Public/Granted literature
- US20100129291A1 NICOTINIC DESENSITIZERS AND METHODS OF SELECTING, TESTING, AND USING THEM Public/Granted day:2010-05-27
Information query
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